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Role of SCN5A coding and non-coding sequences in Brugada syndrome onset: What's behind the scenes?

BACKGROUND: Brugada syndrome (BrS) is a rare inherited cardiac arrhythmia associated with a high risk of sudden cardiac death (SCD) due to ventricular fibrillation (VF). BrS is characterized by coved-type ST-segment elevation in the right precordial leads (V1-V3). Mutations in SCN5A gene coding for...

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Detalles Bibliográficos
Autores principales: Daimi, Houria, Khelil, Amel Haj, Neji, Ali, Ben Hamda, Khaldoun, Maaoui, Sabri, Aranega, Amelia, BE. Chibani, Jemni, Franco, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818142/
https://www.ncbi.nlm.nih.gov/pubmed/31627867
http://dx.doi.org/10.1016/j.bj.2019.03.003