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A Quantitative Model Explains Single-Cell Dynamics of the Adaptive Response in Escherichia coli
DNA damage caused by alkylating chemicals induces an adaptive response in Escherichia coli that increases the tolerance of cells to further damage. Signaling of the response occurs through irreversible methylation of the Ada protein, which acts as a DNA repair protein and damage sensor. Methylated A...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Biophysical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818145/ https://www.ncbi.nlm.nih.gov/pubmed/31466698 http://dx.doi.org/10.1016/j.bpj.2019.08.009 |