The Influence of Molecular Reach and Diffusivity on the Efficacy of Membrane-Confined Reactions

Signaling by surface receptors often relies on tethered reactions whereby an enzyme bound to the cytoplasmic tail of a receptor catalyzes reactions on substrates within reach. The overall length and stiffness of the receptor tail, the enzyme, and the substrate determine a biophysical parameter terme...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Clemens, Lara, Goyette, Jesse, Allard, Jun, Dushek, Omer, Isaacson, Samuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818170/
https://www.ncbi.nlm.nih.gov/pubmed/31543263
http://dx.doi.org/10.1016/j.bpj.2019.08.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818170/
https://www.ncbi.nlm.nih.gov/pubmed/31543263
http://dx.doi.org/10.1016/j.bpj.2019.08.023

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