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SiRNA-Mediated RRM2 Gene Silencing Combined with Cisplatin in the Treatment of Epithelial Ovarian Cancer In Vivo: An Experimental Study of Nude Mice

Introduction: We aimed to explore small interfering (si)RNA silencing of ribonucleotide reductase M2 (RRM2) gene combined with cisplatin for the treatment of human ovarian cancer in nude mice models of subcutaneous transplantation of tumor cells. Methods: After conventional cultivation of human ovar...

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Detalles Bibliográficos
Autores principales: Xue, Ting, Wang, Liming, Li, Yong, Song, Hao, Chu, Huijun, Yang, Hongjuan, Guo, Ailian, Jiao, Jinwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818211/
https://www.ncbi.nlm.nih.gov/pubmed/31673243
http://dx.doi.org/10.7150/ijms.33979