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Molecular Simulations of Intact Anion Exchanger 1 Reveal Specific Domain and Lipid Interactions
Anion exchanger 1 (AE1) is responsible for the exchange of bicarbonate and chloride across the erythrocyte plasma membrane. Human AE1 consists of a cytoplasmic and a membrane domain joined by a 33-residue flexible linker. Crystal structures of the individual domains have been determined, but the int...
Autores principales: | De Vecchis, Dario, Reithmeier, Reinhart A.F., Kalli, Antreas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818359/ https://www.ncbi.nlm.nih.gov/pubmed/31540709 http://dx.doi.org/10.1016/j.bpj.2019.08.029 |
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