Proarrhythmia in the p.Met207Val PITX2c-Linked Familial Atrial Fibrillation-Insights From Modeling

Functional analysis has shown that the p.Met207Val mutation was linked to atrial fibrillation and caused an increase in transactivation activity of PITX2c, which caused changes in mRNA synthesis related to ionic channels and intercellular electrical coupling. We assumed that these changes were quant...

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Detalles Bibliográficos
Autores principales: Bai, Jieyun, Lu, Yaosheng, Lo, Andy, Zhao, Jichao, Zhang, Henggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818469/
https://www.ncbi.nlm.nih.gov/pubmed/31695623
http://dx.doi.org/10.3389/fphys.2019.01314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818469/
https://www.ncbi.nlm.nih.gov/pubmed/31695623
http://dx.doi.org/10.3389/fphys.2019.01314

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