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Interaction Between ITM2B and GLUT9 Links Urate Transport to Neurodegenerative Disorders
Hyperuricemia plays a critical causative role in gout. In contrast, hyperuricemia has a protective effect in neurodegenerative disorders, including Alzheimer’s Disease. Genetic variation in the SLC2A9 gene, encoding the urate transporter GLUT9, exerts the largest single-gene effect on serum uric aci...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818471/ https://www.ncbi.nlm.nih.gov/pubmed/31695625 http://dx.doi.org/10.3389/fphys.2019.01323 |