Cargando…
Interaction Between ITM2B and GLUT9 Links Urate Transport to Neurodegenerative Disorders
Hyperuricemia plays a critical causative role in gout. In contrast, hyperuricemia has a protective effect in neurodegenerative disorders, including Alzheimer’s Disease. Genetic variation in the SLC2A9 gene, encoding the urate transporter GLUT9, exerts the largest single-gene effect on serum uric aci...
Autores principales: | Mandal, Asim K., Mount, David B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818471/ https://www.ncbi.nlm.nih.gov/pubmed/31695625 http://dx.doi.org/10.3389/fphys.2019.01323 |
Ejemplares similares
-
Human Mutations in SLC2A9 (Glut9) Affect Transport Capacity for Urate
por: Ruiz, Anne, et al.
Publicado: (2018) -
Genetic and Physiological Effects of Insulin on Human Urate Homeostasis
por: Mandal, Asim K., et al.
Publicado: (2021) -
Immunohistochemical and in situ hybridization study of urate transporters GLUT9/URATv1, ABCG2, and URAT1 in the murine brain
por: Tomioka, Naoko H., et al.
Publicado: (2016) -
Glucose transporters GLUT1, GLUT3, and GLUT4 have different effects on osteoblast proliferation and metabolism
por: Arponen, Milja, et al.
Publicado: (2022) -
SLC2A9 (GLUT9) mediates urate reabsorption in the mouse kidney
por: Auberson, Muriel, et al.
Publicado: (2018)