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Cell generation dynamics underlying naive T-cell homeostasis in adult humans
Thymic involution and proliferation of naive T cells both contribute to shaping the naive T-cell repertoire as humans age, but a clear understanding of the roles of each throughout a human life span has been difficult to determine. By measuring nuclear bomb test–derived (14)C in genomic DNA, we dete...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818757/ https://www.ncbi.nlm.nih.gov/pubmed/31661488 http://dx.doi.org/10.1371/journal.pbio.3000383 |