Cell generation dynamics underlying naive T-cell homeostasis in adult humans

Thymic involution and proliferation of naive T cells both contribute to shaping the naive T-cell repertoire as humans age, but a clear understanding of the roles of each throughout a human life span has been difficult to determine. By measuring nuclear bomb test–derived (14)C in genomic DNA, we dete...

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Detalles Bibliográficos
Autores principales: Mold, Jeff E., Réu, Pedro, Olin, Axel, Bernard, Samuel, Michaëlsson, Jakob, Rane, Sanket, Yates, Andrew, Khosravi, Azadeh, Salehpour, Mehran, Possnert, Göran, Brodin, Petter, Frisén, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818757/
https://www.ncbi.nlm.nih.gov/pubmed/31661488
http://dx.doi.org/10.1371/journal.pbio.3000383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818757/
https://www.ncbi.nlm.nih.gov/pubmed/31661488
http://dx.doi.org/10.1371/journal.pbio.3000383

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