Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL

T cell acute lymphoblastic leukemia (T-ALL) is a serious hematologic malignancy that occurs in children and young adults. Current therapies include intensive chemotherapy and ionizing radiation that preferentially kill malignant cells. Unfortunately, they are frequently accompanied by unintended neg...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Gundelach, Justin, Lindquist, Lonnie D., Baker, Darren J., van Deursen, Jan, Bram, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818774/
https://www.ncbi.nlm.nih.gov/pubmed/31661505
http://dx.doi.org/10.1371/journal.pone.0224172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818774/
https://www.ncbi.nlm.nih.gov/pubmed/31661505
http://dx.doi.org/10.1371/journal.pone.0224172

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