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Ratiometric GPCR signaling enables directional sensing in yeast

Accurate detection of extracellular chemical gradients is essential for many cellular behaviors. Gradient sensing is challenging for small cells, which can experience little difference in ligand concentrations on the up-gradient and down-gradient sides of the cell. Nevertheless, the tiny cells of th...

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Detalles Bibliográficos
Autores principales: Henderson, Nicholas T., Pablo, Michael, Ghose, Debraj, Clark-Cotton, Manuella R., Zyla, Trevin R., Nolen, James, Elston, Timothy C., Lew, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818790/
https://www.ncbi.nlm.nih.gov/pubmed/31622333
http://dx.doi.org/10.1371/journal.pbio.3000484