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CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro

BACKGROUND AND AIM: The hepatitis C virus (HCV) is a single-strand RNA virus that infects millions of people worldwide. Recent advances in therapy have led to viral cure using two- and three- drug combinations of direct acting inhibitors of viral replication. CCR5 is a chemokine receptor that is exp...

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Detalles Bibliográficos
Autores principales: Blackard, Jason T., Kong, Ling, Rouster, Susan D., Karns, Rebekah, Horn, Paul S., Kottilil, Shyam, Shata, M. Tarek, Sherman, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818973/
https://www.ncbi.nlm.nih.gov/pubmed/31661521
http://dx.doi.org/10.1371/journal.pone.0224523