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Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis

The male-specific region of the Y chromosome (MSY) remains one of the most unexplored regions of the genome. We sought to examine how the genetic variants of the MSY influence male susceptibility to coronary artery disease (CAD) and atherosclerosis. APPROACH AND RESULTS: Analysis of 129 133 men from...

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Detalles Bibliográficos
Autores principales: Eales, James M., Maan, Akhlaq A., Xu, Xiaoguang, Michoel, Tom, Hallast, Pille, Batini, Chiara, Zadik, Daniel, Prestes, Priscilla R., Molina, Elsa, Denniff, Matthew, Schroeder, Juliane, Bjorkegren, Johan L.M., Thompson, John, Maffia, Pasquale, Guzik, Tomasz J., Keavney, Bernard, Jobling, Mark A., Samani, Nilesh J., Charchar, Fadi J., Tomaszewski, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818981/
https://www.ncbi.nlm.nih.gov/pubmed/31644355
http://dx.doi.org/10.1161/ATVBAHA.119.312405