Epigenetic Regulation of Vascular Smooth Muscle Cells by Histone H3 Lysine 9 Dimethylation Attenuates Target Gene-Induction by Inflammatory Signaling

Vascular inflammation underlies cardiovascular disease. Vascular smooth muscle cells (VSMCs) upregulate selective genes, including MMPs (matrix metalloproteinases) and proinflammatory cytokines upon local inflammation, which directly contribute to vascular disease and adverse clinical outcome. Ident...

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Detalles Bibliográficos
Autores principales: Harman, Jennifer L., Dobnikar, Lina, Chappell, Joel, Stokell, Benjamin G., Dalby, Amanda, Foote, Kirsty, Finigan, Alison, Freire-Pritchett, Paula, Taylor, Annabel L., Worssam, Matthew D., Madsen, Ralitsa R., Loche, Elena, Uryga, Anna, Bennett, Martin R., Jørgensen, Helle F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818986/
https://www.ncbi.nlm.nih.gov/pubmed/31434493
http://dx.doi.org/10.1161/ATVBAHA.119.312765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818986/
https://www.ncbi.nlm.nih.gov/pubmed/31434493
http://dx.doi.org/10.1161/ATVBAHA.119.312765

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