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Modelling Macular Edema: The Effect of IL-6 and IL-6R Blockade on Human Blood–Retinal Barrier Integrity In Vitro

PURPOSE: Macular edema (ME) is a leading cause of visual loss in a range of retinal diseases and despite the use of antivascular endothelial growth factor (anti-VEGF) agents, its successful treatment remains a major clinical challenge. Based on the indirect clinical evidence that interleukin-6 (IL-6...

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Detalles Bibliográficos
Autores principales: Mesquida, Marina, Drawnel, Faye, Lait, Philippa J., Copland, David A., Stimpson, Madeleine L., Llorenç, Victor, Sainz de la Maza, Maite, Adan, Alfredo, Widmer, Gabriella, Strassburger, Pamela, Fauser, Sascha, Dick, Andrew D., Lee, Richard W. J., Molins, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819001/
https://www.ncbi.nlm.nih.gov/pubmed/31667008
http://dx.doi.org/10.1167/tvst.8.5.32