Cargando…

Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1

Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder whose neurodevelopmental symptoms include impaired executive function, attention, and spatial learning and could be due to perturbed mesolimbic dopaminergic circuitry. However, these circuits have never been directly assayed in vivo. W...

Descripción completa

Detalles Bibliográficos
Autores principales: Robinson, J Elliott, Coughlin, Gerard M, Hori, Acacia M, Cho, Jounhong Ryan, Mackey, Elisha D, Turan, Zeynep, Patriarchi, Tommaso, Tian, Lin, Gradinaru, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819083/
https://www.ncbi.nlm.nih.gov/pubmed/31545171
http://dx.doi.org/10.7554/eLife.48983