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Dipeptidyl-peptidase-4 (DPP-4) inhibitor ameliorates 5-flurouracil induced intestinal mucositis

BACKGROUND: Chemotherapy-induced alimentary mucositis (AM) is difficult to prevent and treatment is rarely effective. Recent study have been showed that glucagon-like peptide (GLP)-1 and GLP-2 has protective in chemotherapy-induced AM. While the DPP-4 enzyme degrades this GLP-1, the DPP-4 inhibitor...

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Detalles Bibliográficos
Autores principales: Lee, Jung Min, Yoo, In Kyung, Lee, Jae Min, Kim, Seung Han, Choi, Hyuk Soon, Kim, Eun Sun, Keum, Bora, Seo, Yeon Seok, Jeen, Yoon Tae, Chun, Hoon Jai, Lee, Hong Sik, Um, Soon Ho, Kim, Chang Duck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819400/
https://www.ncbi.nlm.nih.gov/pubmed/31664952
http://dx.doi.org/10.1186/s12885-019-6231-y