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Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissues

BACKGROUND: Genomic imprinting is an epigenetic phenomenon that allows a subset of genes to be expressed mono-allelically based on the parent of origin and is typically regulated by differential DNA methylation inherited from gametes. Imprinting is pervasive in murine extra-embryonic lineages, and u...

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Detalles Bibliográficos
Autores principales: Hanna, Courtney W., Pérez-Palacios, Raquel, Gahurova, Lenka, Schubert, Michael, Krueger, Felix, Biggins, Laura, Andrews, Simon, Colomé-Tatché, Maria, Bourc’his, Deborah, Dean, Wendy, Kelsey, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819472/
https://www.ncbi.nlm.nih.gov/pubmed/31665063
http://dx.doi.org/10.1186/s13059-019-1833-x