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Modeling allele-specific expression at the gene and SNP levels simultaneously by a Bayesian logistic mixed regression model

BACKGROUND: High-throughput sequencing experiments, which can determine allele origins, have been used to assess genome-wide allele-specific expression. Despite the amount of data generated from high-throughput experiments, statistical methods are often too simplistic to understand the complexity of...

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Detalles Bibliográficos
Autores principales: Xie, Jing, Ji, Tieming, Ferreira, Marco A. R., Li, Yahan, Patel, Bhaumik N., Rivera, Rocio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819473/
https://www.ncbi.nlm.nih.gov/pubmed/31660858
http://dx.doi.org/10.1186/s12859-019-3141-6