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Modeling allele-specific expression at the gene and SNP levels simultaneously by a Bayesian logistic mixed regression model
BACKGROUND: High-throughput sequencing experiments, which can determine allele origins, have been used to assess genome-wide allele-specific expression. Despite the amount of data generated from high-throughput experiments, statistical methods are often too simplistic to understand the complexity of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819473/ https://www.ncbi.nlm.nih.gov/pubmed/31660858 http://dx.doi.org/10.1186/s12859-019-3141-6 |