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Intratumoral immunoglobulin isotypes predict survival in lung adenocarcinoma subtypes

BACKGROUND: The role of tumor-infiltrating B-cells (TIBs) and intratumorally-produced antibodies in cancer-immunity interactions essentially remains terra incognita. In particular, it remains unexplored how driver mutations could be associated with distinct TIBs signatures and their role in tumor mi...

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Detalles Bibliográficos
Autores principales: Isaeva, O. I., Sharonov, G. V., Serebrovskaya, E. O., Turchaninova, M. A., Zaretsky, A. R., Shugay, M., Chudakov, D. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819482/
https://www.ncbi.nlm.nih.gov/pubmed/31665076
http://dx.doi.org/10.1186/s40425-019-0747-1