BMP3 suppresses colon tumorigenesis via ActRIIB/SMAD2-dependent and TAK1/JNK signaling pathways

BACKGROUND: BMP3 gene is often found hypermethylated and hence inactivated in several types of cancers including colorectal cancer (CRC), indicating that it has a suppressor role in carcinogenesis. Though BMP3 is a reliable biomarker for screening CRC, the molecular mechanism of BMP3 in carcinogenes...

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Detalles Bibliográficos
Autores principales: Wen, Jialing, Liu, Xianglin, Qi, Yan, Niu, Feng, Niu, Zhitong, Geng, Wenjing, Zou, Zhaowei, Huang, Renli, Wang, Jianping, Zou, Hongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819484/
https://www.ncbi.nlm.nih.gov/pubmed/31665064
http://dx.doi.org/10.1186/s13046-019-1435-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819484/
https://www.ncbi.nlm.nih.gov/pubmed/31665064
http://dx.doi.org/10.1186/s13046-019-1435-1

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