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Potential therapeutic effects of cyanidin-3-O-glucoside on rheumatoid arthritis by relieving inhibition of CD38+ NK cells on Treg cell differentiation

BACKGROUND: CD38+ NK cells are overabundant in rheumatoid arthritis (RA). Cyanidin-3-O-glucoside (C3G) is an inhibitor of CD38. This study investigated the pathogenic role of CD38+ NK cells and the effect of C3G on RA. METHODS: Rats with bovine type II collagen-induced arthritis (CIA) were injected...

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Detalles Bibliográficos
Autores principales: Wang, Hongxing, Li, Shutong, Zhang, Guoqing, Wu, Hui, Chang, Xiaotian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819496/
https://www.ncbi.nlm.nih.gov/pubmed/31661005
http://dx.doi.org/10.1186/s13075-019-2001-0