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Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative condition that primarily affects the motor system and shares many features with frontotemporal dementia (FTD). Evidence suggests that ALS is a ‘dying-back’ disease, with peripheral denervation and axonal degeneration occurring before l...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819591/ https://www.ncbi.nlm.nih.gov/pubmed/31661035 http://dx.doi.org/10.1186/s40478-019-0800-9 |