Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative condition that primarily affects the motor system and shares many features with frontotemporal dementia (FTD). Evidence suggests that ALS is a ‘dying-back’ disease, with peripheral denervation and axonal degeneration occurring before l...

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Detalles Bibliográficos
Autores principales: White, Matthew A., Lin, Ziqiang, Kim, Eugene, Henstridge, Christopher M., Pena Altamira, Emiliano, Hunt, Camille K., Burchill, Ella, Callaghan, Isobel, Loreto, Andrea, Brown-Wright, Heledd, Mead, Richard, Simmons, Camilla, Cash, Diana, Coleman, Michael P., Sreedharan, Jemeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819591/
https://www.ncbi.nlm.nih.gov/pubmed/31661035
http://dx.doi.org/10.1186/s40478-019-0800-9

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