JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathway

BACKGROUND: Our previous work demonstrated that lncRNA-MALAT1 was overexpressed in recurrent colorectal cancer (CRC) and metastatic sites in post-surgical patients. However, the upstream regulatory mechanism of MALAT1 is not well-defined. Histone demethylase JMJD2C holds great potential of epigeneti...

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Detalles Bibliográficos
Autores principales: Wu, Xinnan, Li, Ruixiao, Song, Qing, Zhang, Chengcheng, Jia, Ru, Han, Zhifen, Zhou, Lihong, Sui, Hua, Liu, Xuan, Zhu, Huirong, Yang, Liu, Wang, Yan, Ji, Qing, Li, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819649/
https://www.ncbi.nlm.nih.gov/pubmed/31665047
http://dx.doi.org/10.1186/s13046-019-1439-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819649/
https://www.ncbi.nlm.nih.gov/pubmed/31665047
http://dx.doi.org/10.1186/s13046-019-1439-x

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