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Steroidogenic control of liver metabolism through a nuclear receptor-network

OBJECTIVE: Coupling metabolic and reproductive pathways is essential for the survival of species. However, the functions of steroidogenic enzymes expressed in metabolic tissues are largely unknown. METHODS AND RESULTS: Here, we show that in the liver, the classical steroidogenic enzyme Cyp17a1 forms...

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Detalles Bibliográficos
Autores principales: Milona, Alexandra, Massafra, Vittoria, Vos, Harmjan, Naik, Jyoti, Artigas, Natalia, Paterson, Helen A.B., Bijsmans, Ingrid T.G.W., Willemsen, Ellen C.L., Ramos Pittol, Jose M., Miguel-Aliaga, Irene, Bosma, Piter, Burgering, Boudewijn M.T., Williamson, Catherine, Vernia, Santiago, Dhillo, Waljit S., van Mil, Saskia W.C., Owen, Bryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819870/
https://www.ncbi.nlm.nih.gov/pubmed/31767173
http://dx.doi.org/10.1016/j.molmet.2019.09.007