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Role of nociceptin/orphanin FQ and nociceptin opioid peptide receptor in depression and antidepressant effects of nociceptin opioid peptide receptor antagonists

Nociceptin/orphanin FQ (N/OFQ) and its receptor, nociceptin opioid peptide (NOP) receptor, are localized in brain areas implicated in depression including the amygdala, bed nucleus of the stria terminalis, habenula, and monoaminergic nuclei in the brain stem. N/OFQ inhibits neuronal excitability of...

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Detalles Bibliográficos
Autores principales: Park, Jong Yung, Chae, Suji, Kim, Chang Seop, Kim, Yoon Jae, Yi, Hyun Joo, Han, Eunjoo, Joo, Youngshin, Hong, Surim, Yun, Jae Won, Kim, Hyojung, Shin, Kyung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819898/
https://www.ncbi.nlm.nih.gov/pubmed/31680765
http://dx.doi.org/10.4196/kjpp.2019.23.6.427