The potential of dendrimer in delivery of therapeutics for dentistry

Dendrimers are hyperbranched nanoparticle structures along with its surface modifications can to be used in dental biomaterials for biomimetic remineralisation of enamel and dentin. The review highlights the therapeutic applications of dendrimers in the field of dentistry. It addresses the possible...

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Autores principales: Bapat, Ranjeet A., Dharmadhikari, Suyog, Chaubal, Tanay V., Amin, Mohd Cairul Iqbal Mohd, Bapat, Prachi, Gorain, Bapi, Choudhury, Hira, Vincent, Christopher, Kesharwani, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820096/
https://www.ncbi.nlm.nih.gov/pubmed/31687479
http://dx.doi.org/10.1016/j.heliyon.2019.e02544
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author Bapat, Ranjeet A.
Dharmadhikari, Suyog
Chaubal, Tanay V.
Amin, Mohd Cairul Iqbal Mohd
Bapat, Prachi
Gorain, Bapi
Choudhury, Hira
Vincent, Christopher
Kesharwani, Prashant
author_facet Bapat, Ranjeet A.
Dharmadhikari, Suyog
Chaubal, Tanay V.
Amin, Mohd Cairul Iqbal Mohd
Bapat, Prachi
Gorain, Bapi
Choudhury, Hira
Vincent, Christopher
Kesharwani, Prashant
author_sort Bapat, Ranjeet A.
collection PubMed
description Dendrimers are hyperbranched nanoparticle structures along with its surface modifications can to be used in dental biomaterials for biomimetic remineralisation of enamel and dentin. The review highlights the therapeutic applications of dendrimers in the field of dentistry. It addresses the possible mechanisms of enhancement of mechanical properties of adhesives and resins structure. Dendrimers due to its unique construction of possessing inner hydrophobic and outer hydrophilic structure can act as drug carrier for delivery of antimicrobial drugs for treatment of periodontal diseases and at peripheral dental implant areas. Dendrimers due to its hyperbranched structures can provides a unique drug delivery vehicle for delivery of a drug at specific site for sustained release for therapeutic effects. Thus, dendrimers can be one of the most important constituents which can be incorporated in dental biomaterials for better outcomes in dentistry.
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spelling pubmed-68200962019-11-04 The potential of dendrimer in delivery of therapeutics for dentistry Bapat, Ranjeet A. Dharmadhikari, Suyog Chaubal, Tanay V. Amin, Mohd Cairul Iqbal Mohd Bapat, Prachi Gorain, Bapi Choudhury, Hira Vincent, Christopher Kesharwani, Prashant Heliyon Article Dendrimers are hyperbranched nanoparticle structures along with its surface modifications can to be used in dental biomaterials for biomimetic remineralisation of enamel and dentin. The review highlights the therapeutic applications of dendrimers in the field of dentistry. It addresses the possible mechanisms of enhancement of mechanical properties of adhesives and resins structure. Dendrimers due to its unique construction of possessing inner hydrophobic and outer hydrophilic structure can act as drug carrier for delivery of antimicrobial drugs for treatment of periodontal diseases and at peripheral dental implant areas. Dendrimers due to its hyperbranched structures can provides a unique drug delivery vehicle for delivery of a drug at specific site for sustained release for therapeutic effects. Thus, dendrimers can be one of the most important constituents which can be incorporated in dental biomaterials for better outcomes in dentistry. Elsevier 2019-10-23 /pmc/articles/PMC6820096/ /pubmed/31687479 http://dx.doi.org/10.1016/j.heliyon.2019.e02544 Text en © 2019 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Bapat, Ranjeet A.
Dharmadhikari, Suyog
Chaubal, Tanay V.
Amin, Mohd Cairul Iqbal Mohd
Bapat, Prachi
Gorain, Bapi
Choudhury, Hira
Vincent, Christopher
Kesharwani, Prashant
The potential of dendrimer in delivery of therapeutics for dentistry
title The potential of dendrimer in delivery of therapeutics for dentistry
title_full The potential of dendrimer in delivery of therapeutics for dentistry
title_fullStr The potential of dendrimer in delivery of therapeutics for dentistry
title_full_unstemmed The potential of dendrimer in delivery of therapeutics for dentistry
title_short The potential of dendrimer in delivery of therapeutics for dentistry
title_sort potential of dendrimer in delivery of therapeutics for dentistry
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820096/
https://www.ncbi.nlm.nih.gov/pubmed/31687479
http://dx.doi.org/10.1016/j.heliyon.2019.e02544
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