The potential of dendrimer in delivery of therapeutics for dentistry
Dendrimers are hyperbranched nanoparticle structures along with its surface modifications can to be used in dental biomaterials for biomimetic remineralisation of enamel and dentin. The review highlights the therapeutic applications of dendrimers in the field of dentistry. It addresses the possible...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820096/ https://www.ncbi.nlm.nih.gov/pubmed/31687479 http://dx.doi.org/10.1016/j.heliyon.2019.e02544 |
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author | Bapat, Ranjeet A. Dharmadhikari, Suyog Chaubal, Tanay V. Amin, Mohd Cairul Iqbal Mohd Bapat, Prachi Gorain, Bapi Choudhury, Hira Vincent, Christopher Kesharwani, Prashant |
author_facet | Bapat, Ranjeet A. Dharmadhikari, Suyog Chaubal, Tanay V. Amin, Mohd Cairul Iqbal Mohd Bapat, Prachi Gorain, Bapi Choudhury, Hira Vincent, Christopher Kesharwani, Prashant |
author_sort | Bapat, Ranjeet A. |
collection | PubMed |
description | Dendrimers are hyperbranched nanoparticle structures along with its surface modifications can to be used in dental biomaterials for biomimetic remineralisation of enamel and dentin. The review highlights the therapeutic applications of dendrimers in the field of dentistry. It addresses the possible mechanisms of enhancement of mechanical properties of adhesives and resins structure. Dendrimers due to its unique construction of possessing inner hydrophobic and outer hydrophilic structure can act as drug carrier for delivery of antimicrobial drugs for treatment of periodontal diseases and at peripheral dental implant areas. Dendrimers due to its hyperbranched structures can provides a unique drug delivery vehicle for delivery of a drug at specific site for sustained release for therapeutic effects. Thus, dendrimers can be one of the most important constituents which can be incorporated in dental biomaterials for better outcomes in dentistry. |
format | Online Article Text |
id | pubmed-6820096 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-68200962019-11-04 The potential of dendrimer in delivery of therapeutics for dentistry Bapat, Ranjeet A. Dharmadhikari, Suyog Chaubal, Tanay V. Amin, Mohd Cairul Iqbal Mohd Bapat, Prachi Gorain, Bapi Choudhury, Hira Vincent, Christopher Kesharwani, Prashant Heliyon Article Dendrimers are hyperbranched nanoparticle structures along with its surface modifications can to be used in dental biomaterials for biomimetic remineralisation of enamel and dentin. The review highlights the therapeutic applications of dendrimers in the field of dentistry. It addresses the possible mechanisms of enhancement of mechanical properties of adhesives and resins structure. Dendrimers due to its unique construction of possessing inner hydrophobic and outer hydrophilic structure can act as drug carrier for delivery of antimicrobial drugs for treatment of periodontal diseases and at peripheral dental implant areas. Dendrimers due to its hyperbranched structures can provides a unique drug delivery vehicle for delivery of a drug at specific site for sustained release for therapeutic effects. Thus, dendrimers can be one of the most important constituents which can be incorporated in dental biomaterials for better outcomes in dentistry. Elsevier 2019-10-23 /pmc/articles/PMC6820096/ /pubmed/31687479 http://dx.doi.org/10.1016/j.heliyon.2019.e02544 Text en © 2019 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Bapat, Ranjeet A. Dharmadhikari, Suyog Chaubal, Tanay V. Amin, Mohd Cairul Iqbal Mohd Bapat, Prachi Gorain, Bapi Choudhury, Hira Vincent, Christopher Kesharwani, Prashant The potential of dendrimer in delivery of therapeutics for dentistry |
title | The potential of dendrimer in delivery of therapeutics for dentistry |
title_full | The potential of dendrimer in delivery of therapeutics for dentistry |
title_fullStr | The potential of dendrimer in delivery of therapeutics for dentistry |
title_full_unstemmed | The potential of dendrimer in delivery of therapeutics for dentistry |
title_short | The potential of dendrimer in delivery of therapeutics for dentistry |
title_sort | potential of dendrimer in delivery of therapeutics for dentistry |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820096/ https://www.ncbi.nlm.nih.gov/pubmed/31687479 http://dx.doi.org/10.1016/j.heliyon.2019.e02544 |
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