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Development of a new and reliable assay for choline kinase using (31)P NMR

Choline kinase catalyzes the conversion of choline to phosphocholine (PC) by transferring a phosphate group from adenosine triphosphate (ATP) as the first step in the biosynthetic pathway for the membrane phospholipid phosphatidylcholine, an essential pathway in the Leishmania parasitic protozoan. C...

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Detalles Bibliográficos
Autores principales: Walker, Jacob A., Friesen, Joshua D., Peters, Steven J., Jones, Marjorie A., Friesen, Jon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820101/
https://www.ncbi.nlm.nih.gov/pubmed/31687487
http://dx.doi.org/10.1016/j.heliyon.2019.e02585