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Higher CSF Tau Levels Are Related to Hippocampal Hyperactivity and Object Mnemonic Discrimination in Older Adults

Mnemonic discrimination, the ability to distinguish similar events in memory, relies on subregions in the human medial temporal lobes (MTLs). Tau pathology is frequently found within the MTL of older adults and therefore likely to affect mnemonic discrimination, even in healthy older individuals. Th...

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Detalles Bibliográficos
Autores principales: Berron, David, Cardenas-Blanco, Arturo, Bittner, Daniel, Metzger, Coraline D., Spottke, Annika, Heneka, Michael T., Fliessbach, Klaus, Schneider, Anja, Teipel, Stefan J., Wagner, Michael, Speck, Oliver, Jessen, Frank, Düzel, Emrah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820211/
https://www.ncbi.nlm.nih.gov/pubmed/31541019
http://dx.doi.org/10.1523/JNEUROSCI.1279-19.2019