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Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury

Genetic porphyrias comprise eight diseases caused by defects in the heme biosynthetic pathway that lead to accumulation of heme precursors. Consequences of porphyria include photosensitivity, liver damage and increased risk of hepatocellular carcinoma, and neurovisceral involvement, including seizur...

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Detalles Bibliográficos
Autores principales: Maitra, Dhiman, Bragazzi Cunha, Juliana, Elenbaas, Jared S., Bonkovsky, Herbert L., Shavit, Jordan A., Omary, M. Bishr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820234/
https://www.ncbi.nlm.nih.gov/pubmed/31233899
http://dx.doi.org/10.1016/j.jcmgh.2019.06.006