WRNIP1 Protects Reversed DNA Replication Forks from SLX4-Dependent Nucleolytic Cleavage

During DNA replication stress, stalled replication forks need to be stabilized to prevent fork collapse and genome instability. The AAA + ATPase WRNIP1 (Werner Helicase Interacting Protein 1) has been implicated in the protection of stalled replication forks from nucleolytic degradation, but the und...

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Detalles Bibliográficos
Autores principales: Porebski, Bartlomiej, Wild, Sebastian, Kummer, Sandra, Scaglione, Sarah, Gaillard, Pierre-Henri L., Gari, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820244/
https://www.ncbi.nlm.nih.gov/pubmed/31654852
http://dx.doi.org/10.1016/j.isci.2019.10.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820244/
https://www.ncbi.nlm.nih.gov/pubmed/31654852
http://dx.doi.org/10.1016/j.isci.2019.10.010

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