Cargando…

TGF-β induces a heart failure phenotype via fibroblasts exosome signaling

PURPOSE: The mechanisms for persistent and progressive loss of myocardial function in advanced heart failure (HF) remain incompletely characterized. In the current study, we sought to determine the impact of TGF-β on fibroblasts transcriptional profiles and assess if exosomes from TGF-β treated fibr...

Descripción completa

Detalles Bibliográficos
Autores principales: Basma, Hesham, Johanson, Adelaide N., Dhar, Kajari, Anderson, Daniel, Qiu, Fang, Rennard, Stephen, Lowes, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820308/
https://www.ncbi.nlm.nih.gov/pubmed/31687497
http://dx.doi.org/10.1016/j.heliyon.2019.e02633