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Effect of Intravenous Lipid Emulsion on Clozapine Acute Toxicity in Rats

OBJECTIVES: Many studies have been reported the efficacy of intravenous lipid emulsion (ILE) as an antidote on acute lipophilic drug toxicity. Clozapine, highly lipophilic dibenzodiazepine neuroleptics, is an important medication in the schizophrenia therapy regimen. Acute intoxication with antipsyc...

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Detalles Bibliográficos
Autores principales: Yousefsani, Bahareh Sadat, Mohajeri, Seyed Ahmad, Moshiri, Mohammad, Jafarian, Amir Hossein, Hosseinzadeh, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pharmacopuncture Institute (KPI) 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820469/
https://www.ncbi.nlm.nih.gov/pubmed/31673444
http://dx.doi.org/10.3831/KPI.2019.22.019