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Low Intensity Focused Ultrasound (LOFU)-mediated Acoustic Immune Priming and Ablative Radiation Therapy for in situ Tumor Vaccines

Focal ablative therapies have been primarily used for local tumor ablation. However, they often fail to impact systemic disease. Here we propose the use of low intensity focused ultrasound (LOFU), a noninvasive, nontoxic, conformal therapy, to deliver acoustic stress to the tumor for immune priming....

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Detalles Bibliográficos
Autores principales: Skalina, Karin A., Singh, Saurabh, Chavez, Claudia Gutierrez, Macian, Fernando, Guha, Chandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820551/
https://www.ncbi.nlm.nih.gov/pubmed/31664044
http://dx.doi.org/10.1038/s41598-019-51332-4