TAF1 plays a critical role in AML1-ETO driven leukemogenesis

AML1-ETO (AE) is a fusion transcription factor, generated by the t(8;21) translocation, that functions as a leukemia promoting oncogene. Here, we demonstrate that TATA-Box Binding Protein Associated Factor 1 (TAF1) associates with K43 acetylated AE and this association plays a pivotal role in the pr...

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Detalles Bibliográficos
Autores principales: Xu, Ye, Man, Na, Karl, Daniel, Martinez, Concepcion, Liu, Fan, Sun, Jun, Martinez, Camilo Jose, Martin, Gloria Mas, Beckedorff, Felipe, Lai, Fan, Yue, Jingyin, Roisman, Alejandro, Greenblatt, Sarah, Duffort, Stephanie, Wang, Lan, Sun, Xiaojian, Figueroa, Maria, Shiekhattar, Ramin, Nimer, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820555/
https://www.ncbi.nlm.nih.gov/pubmed/31664040
http://dx.doi.org/10.1038/s41467-019-12735-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820555/
https://www.ncbi.nlm.nih.gov/pubmed/31664040
http://dx.doi.org/10.1038/s41467-019-12735-z

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