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Aβ modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism
Emerging evidences suggest that phospholipid metabolism is altered in Alzheimer’s disease (AD), but molecular mechanisms on how this affects neurodegeneration in AD is poorly understood. SHIP2 is a phosphoinositide-metabolizing enzyme, which dephosphorylates PI(3,4,5)P(3) resulting to PI(3,4)P(2), a...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820556/ https://www.ncbi.nlm.nih.gov/pubmed/31664099 http://dx.doi.org/10.1038/s41598-019-51914-2 |