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Network vulnerability-based and knowledge-guided identification of microRNA biomarkers indicating platinum resistance in high-grade serous ovarian cancer

BACKGROUND: High-grade serous ovarian cancer (HGSC), the most common ovarian carcinoma type, is associated with the highest mortality rate among all gynecological malignancies. As chemoresistance has been demonstrated as the major challenge in improving the prognosis of HGSC patients, we here aimed...

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Detalles Bibliográficos
Autores principales: Qi, Xin, Yu, Chunjiang, Wang, Yi, Lin, Yuxin, Shen, Bairong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820656/
https://www.ncbi.nlm.nih.gov/pubmed/31664600
http://dx.doi.org/10.1186/s40169-019-0245-6