Detecting TP53 mutations in diagnostic and archival liquid-based Pap samples from ovarian cancer patients using an ultra-sensitive ddPCR method

High-grade serous ovarian cancer (HGSOC) is the most common subtype of epithelial ovarian cancer and early detection is challenging. TP53 mutations are a hallmark of HGSOC and detection of these mutations in liquid-based Pap samples could provide a method for early diagnosis. Here we evaluate the us...

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Detalles Bibliográficos
Autores principales: Arildsen, Nicolai Skovbjerg, Martin de la Fuente, Laura, Måsbäck, Anna, Malander, Susanne, Forslund, Ola, Kannisto, Päivi, Hedenfalk, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820715/
https://www.ncbi.nlm.nih.gov/pubmed/31664085
http://dx.doi.org/10.1038/s41598-019-51697-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820715/
https://www.ncbi.nlm.nih.gov/pubmed/31664085
http://dx.doi.org/10.1038/s41598-019-51697-6

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