Automatic structure-based NMR methyl resonance assignment in large proteins

Isotopically labeled methyl groups provide NMR probes in large, otherwise deuterated proteins. However, the resonance assignment constitutes a bottleneck for broader applicability of methyl-based NMR. Here, we present the automated MethylFLYA method for the assignment of methyl groups that is based...

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Detalles Bibliográficos
Autores principales: Pritišanac, Iva, Würz, Julia M., Alderson, T. Reid, Güntert, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820720/
https://www.ncbi.nlm.nih.gov/pubmed/31664028
http://dx.doi.org/10.1038/s41467-019-12837-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820720/
https://www.ncbi.nlm.nih.gov/pubmed/31664028
http://dx.doi.org/10.1038/s41467-019-12837-8

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