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Actomyosin contractility scales with myoblast elongation and enhances differentiation through YAP nuclear export
Skeletal muscle fibers are formed by the fusion of mononucleated myoblasts into long linear myotubes, which differentiate and reorganize into multinucleated myofibers that assemble in bundles to form skeletal muscles. This fundamental process requires the elongation of myoblasts into a bipolar shape...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820726/ https://www.ncbi.nlm.nih.gov/pubmed/31664178 http://dx.doi.org/10.1038/s41598-019-52129-1 |