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Actomyosin contractility scales with myoblast elongation and enhances differentiation through YAP nuclear export

Skeletal muscle fibers are formed by the fusion of mononucleated myoblasts into long linear myotubes, which differentiate and reorganize into multinucleated myofibers that assemble in bundles to form skeletal muscles. This fundamental process requires the elongation of myoblasts into a bipolar shape...

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Detalles Bibliográficos
Autores principales: Bruyère, Céline, Versaevel, Marie, Mohammed, Danahe, Alaimo, Laura, Luciano, Marine, Vercruysse, Eléonore, Gabriele, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820726/
https://www.ncbi.nlm.nih.gov/pubmed/31664178
http://dx.doi.org/10.1038/s41598-019-52129-1