Novel dihydroartemisinin dimer containing nitrogen atoms inhibits growth of endometrial cancer cells and may correlate with increasing intracellular peroxynitrite

In the present study, a novel dimer, SM1044, selected from a series of dihydroartemisinin (DHA) derivatives containing nitrogen atoms comprising simple aliphatic amine linkers, showed strong growth inhibition in six types of human endometrial cancer (EC) cells, with half maximal inhibitory concentra...

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Detalles Bibliográficos
Autores principales: Zhu, Yan, Klausen, Christian, Zhou, Jieyun, Guo, Xiangjie, Zhang, Yu, Zhu, Hua, Li, Zhao, Cheng, Jung-Chien, Xie, Shuwu, Yang, Wenjie, Li, Ying, Leung, Peter C. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820742/
https://www.ncbi.nlm.nih.gov/pubmed/31664127
http://dx.doi.org/10.1038/s41598-019-52108-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820742/
https://www.ncbi.nlm.nih.gov/pubmed/31664127
http://dx.doi.org/10.1038/s41598-019-52108-6

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