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Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells

Osteopontin (OPN) plays a role in inflammation via recruitment of neutrophils and tissue remodeling. In this study, we investigated the distribution of OPN-expressing cells in the airway epithelium of normal lung tissue and that from patients with chronic obstructive pulmonary disease (COPD). OPN wa...

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Detalles Bibliográficos
Autores principales: Ali, Mohamad N., Mori, Michiko, Mertens, Tinne C. J., Siddhuraj, Premkumar, Erjefält, Jonas S., Önnerfjord, Patrik, Hiemstra, Pieter S., Egesten, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820743/
https://www.ncbi.nlm.nih.gov/pubmed/31664154
http://dx.doi.org/10.1038/s41598-019-52208-3