IRAK3 modulates downstream innate immune signalling through its guanylate cyclase activity

Interleukin-1 receptor associated kinase 3 (IRAK3) is a cytoplasmic homeostatic mediator of inflammatory responses and is potentially useful as a prognostic marker in inflammation. IRAK3 inhibits signalling cascades downstream of myddosome complexes associated with toll like receptors. IRAK3 contain...

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Detalles Bibliográficos
Autores principales: Freihat, L. A., Wheeler, J. I., Wong, A., Turek, I., Manallack, D. T., Irving, H. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820782/
https://www.ncbi.nlm.nih.gov/pubmed/31664109
http://dx.doi.org/10.1038/s41598-019-51913-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820782/
https://www.ncbi.nlm.nih.gov/pubmed/31664109
http://dx.doi.org/10.1038/s41598-019-51913-3

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