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LXRβ controls glioblastoma cell growth, lipid balance, and immune modulation independently of ABCA1

Cholesterol is a critical component of membranes and a precursor for hormones and other signaling molecules. Previously, we showed that unlike astrocytes, glioblastoma cells do not downregulate cholesterol synthesis when plated at high density. In this report, we show that high cell density induces...

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Detalles Bibliográficos
Autores principales: Patel, Deven, Ahmad, Fahim, Kambach, Diane M., Sun, Qian, Halim, Alan S., Kramp, Tamalee, Camphausen, Kevin A., Stommel, Jayne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820787/
https://www.ncbi.nlm.nih.gov/pubmed/31664073
http://dx.doi.org/10.1038/s41598-019-51865-8