Cargando…

Investigation of factors that cause insulin precipitation and/or amyloid formation in insulin formulations

BACKGROUND: Multiple daily subcutaneous injections (MDSIs) are mainly used for formulating an insulin therapy for diabetic patients; however, they also cause insulin-derived amyloidosis (IDA) and lead to poor glycemic control. In addition, for the continuous subcutaneous insulin infusion system (CSI...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohno, Yui, Seki, Tomohiro, Kojima, Yu, Miki, Ryotaro, Egawa, Yuya, Hosoya, Osamu, Kasono, Keizo, Seki, Toshinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820959/
https://www.ncbi.nlm.nih.gov/pubmed/31687164
http://dx.doi.org/10.1186/s40780-019-0151-5