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Investigation of factors that cause insulin precipitation and/or amyloid formation in insulin formulations

BACKGROUND: Multiple daily subcutaneous injections (MDSIs) are mainly used for formulating an insulin therapy for diabetic patients; however, they also cause insulin-derived amyloidosis (IDA) and lead to poor glycemic control. In addition, for the continuous subcutaneous insulin infusion system (CSI...

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Detalles Bibliográficos
Autores principales:	Ohno, Yui, Seki, Tomohiro, Kojima, Yu, Miki, Ryotaro, Egawa, Yuya, Hosoya, Osamu, Kasono, Keizo, Seki, Toshinobu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820959/ https://www.ncbi.nlm.nih.gov/pubmed/31687164 http://dx.doi.org/10.1186/s40780-019-0151-5

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