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Predicting protein inter-residue contacts using composite likelihood maximization and deep learning

BACKGROUND: Accurate prediction of inter-residue contacts of a protein is important to calculating its tertiary structure. Analysis of co-evolutionary events among residues has been proved effective in inferring inter-residue contacts. The Markov random field (MRF) technique, although being widely u...

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Detalles Bibliográficos
Autores principales: Zhang, Haicang, Zhang, Qi, Ju, Fusong, Zhu, Jianwei, Gao, Yujuan, Xie, Ziwei, Deng, Minghua, Sun, Shiwei, Zheng, Wei-Mou, Bu, Dongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821021/
https://www.ncbi.nlm.nih.gov/pubmed/31664895
http://dx.doi.org/10.1186/s12859-019-3051-7