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Monotherapy versus combination therapy for multidrug-resistant Gram-negative infections: Systematic Review and Meta-Analysis

Infections caused by carbapenemase-producing, multidrug-resistant (MDR), or extensively drug-resistant (XDR) Gram-negative bacteria constitute a major therapeutic challenge. Whether combination antibiotic therapy is superior to monotherapy remains unknown. In this systematic review and meta-analysis...

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Detalles Bibliográficos
Autores principales: Schmid, Adrian, Wolfensberger, Aline, Nemeth, Johannes, Schreiber, Peter W., Sax, Hugo, Kuster, Stefan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821042/
https://www.ncbi.nlm.nih.gov/pubmed/31664064
http://dx.doi.org/10.1038/s41598-019-51711-x