The herpes simplex virus host shutoff (vhs) RNase limits accumulation of double stranded RNA in infected cells: Evidence for accelerated decay of duplex RNA

The herpes simplex virus virion host shutoff (vhs) RNase destabilizes cellular and viral mRNAs and blunts host innate antiviral responses. Previous work demonstrated that cells infected with vhs mutants display enhanced activation of the host double-stranded RNA (dsRNA)-activated protein kinase R (P...

Descripción completa

Detalles Bibliográficos
Autores principales: Dauber, Bianca, Saffran, Holly A., Smiley, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821131/
https://www.ncbi.nlm.nih.gov/pubmed/31626661
http://dx.doi.org/10.1371/journal.ppat.1008111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821131/
https://www.ncbi.nlm.nih.gov/pubmed/31626661
http://dx.doi.org/10.1371/journal.ppat.1008111

Ejemplares similares